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KMID : 0616120160470040374
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Korean Journal of Pharmacognosy
2016 Volume.47 No. 4 p.374 ~ p.380
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Quality Variation of Sibjeondaebotang according to Long-term Storage
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Kim Ae-Kyung
Lee Chun-Yeong
Hwang Kwang-Ho
Lee Young-Jong
Kim Su-Jin
Lee Young-Ju
Lee Hyun-Kyung
Lee Sae-Ram
Kim Il-Young
Lee Jeong-Mi
Yoo In-Sil
Jung Kweon
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Abstract
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The purpose of this study was to evaluate of quality variation of Sibujeondaebotang according to storage period and temperature (5 and 25℃) Identificaion test, pH, specific gravity, heavy metal, microbial limit test and glycyrrhizic acid, pae-oniflorin content of Sibjeondaebotang were performed during 12 months. The significant change was not shown on iden-tificaion test, specific gravity, microbial limit test under long term storage and the result suited a safe level standards of `Korean National Standard of Traditional Medicinal (Herbal and Botanical) Materials - “Sibjeondaebotang”`. The test of pH showed meaningful changes between two storage temperature (5 and 25℃) according to increasing storage period. The contents of gly-cyrrhizic acid and paeoniflorin had no relation with storage temperature(5℃, 25℃) but it showed a tendency to decrease according to the length of storage period. We predicted shelf-life of glycyrrhizic acid and paeoniflorin at storgae temperature(5 and 25℃) as about 6 and 3 months, respecttively. Therefore considering glycyrrhizic acid and paeoniflorin, sibjeondaebotang is determined to be in good condition within 3 months, regardless of the room temperature and refrigerated temperature. We were expected to serve as a basis for the guideline of medication counseling sibjeondaebotang.
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KEYWORD
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Sibjeondaebotang, Glycyrrhizic acid, Paeoniflorin, Long-term Storage
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